A Splicing Mutation in the Novel Mitochondrial Protein DNAJC11 Causes Motor Neuron Pathology Associated with Cristae Disorganization, and Lymphoid Abnormalities in Mice

Mitochondrial structure and function is emerging as a major contributor to neuromuscular disease, highlighting the need for the complete elucidation of the underlying molecular and pathophysiological mechanisms. Following a forward genetics approach with N-ethyl-N-nitrosourea (ENU)-mediated random m...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ioakeimidis, Fotis, Ott, Christine, Kozjak-Pavlovic, Vera, Violitzi, Foteini, Rinotas, Vagelis, Makrinou, Eleni, Eliopoulos, Elias, Fasseas, Costas, Kollias, George, Douni, Eleni
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128653/
https://ncbi.nlm.nih.gov/pubmed/25111180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104237
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires