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Kinetic model facilitates analysis of fibrin generation and its modulation by clotting factors: implications for hemostasis-enhancing therapies()

Current mechanistic knowledge of protein interactions driving blood coagulation has come largely from experiments with simple synthetic systems, which only partially represent the molecular composition of human blood plasma. Here, we investigate the ability of the suggested molecular mechanisms to a...

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Autors principals: Mitrophanov, Alexander Y., Wolberg, Alisa S., Reifman, Jaques
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128477/
https://ncbi.nlm.nih.gov/pubmed/24958246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4mb00263f
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