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Chronic Knockdown of the NTS AT1R Increases Blood Inflammatory-Endothelial Progenitor Cells Ratio and Exacerbates Hypertension in the SHR

AT1 receptor subtype a (AT1R1a) expression is increased in the nucleus of the solitary tract (NTS) in Spontaneously Hypertensive Rat (SHR) compared to Wistar Kyoto (WKY) controls. However, the chronic role of AT1Ra in the NTS for cardiovascular control is not well understood. In this study, we inves...

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Autors principals: Shan, Zhiying, Zubcevic, Jasenka, Shi, Peng, Jun, Joo Yun, Dong, Ying, Murça, Tatiane M., Lamont, Gwyneth J., Cuadra, Adolfo, Yuan, Wei, Qi, Yanfei, Li, Qiuhong, Paton, Julian FR, Katovich, Michael J, Sumners, Colin, Raizada, Mohan K.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128231/
https://ncbi.nlm.nih.gov/pubmed/23547238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.00156
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