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mTOR signaling inhibition modulates macrophages/microglia-mediated neuroinflammation and secondary injury via regulatory T cells after focal ischemia
Signaling by the mammalian target of rapamycin (mTOR) plays an important role in the modulation of both innate and adaptive immune responses. However, the role and underlying mechanism of mTOR signaling in post-stroke neuroinflammation is largely unexplored. Here, we injected rapamycin, an mTOR inhi...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4128178/ https://ncbi.nlm.nih.gov/pubmed/24829408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303492 |
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