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Encapsidated hepatitis B virus reverse transcriptase is poised on an ordered RNA lattice

Assembly of a hepatitis B virus (HBV) virion begins with the formation of an RNA-filled core composed of a symmetrical capsid (built of core protein), viral pregenomic RNA, and viral reverse transcriptase. To generate the circular dsDNA genome of HBV, reverse transcription requires multiple template...

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Detalhes bibliográficos
Main Authors: Wang, Joseph Che-Yen, Nickens, David G., Lentz, Thomas B., Loeb, Daniel D., Zlotnick, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128116/
https://ncbi.nlm.nih.gov/pubmed/25034253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321424111
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