Mutation of the principal sigma factor causes loss of virulence in a strain of the Mycobacterium tuberculosis complex.
Tuberculosis continues to be responsible for the deaths of millions of people, yet the virulence factors of the causative pathogens remain unknown. Genetic complementation experiments with strains of the Mycobacterium tuberculosis complex have identified a gene from a virulent strain that restores v...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1995
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41281/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7644534/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.17.8036 |
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