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Modulation of transglutaminase 2 activity in H9c2 cells by PKC and PKA signalling: a role for transglutaminase 2 in cytoprotection

BACKGROUND AND PURPOSE: Tissue transglutaminase (TG2) has been shown to mediate cell survival in many cell types. In this study, we investigated whether the role of TG2 in cytoprotection was mediated by the activation of PKA and PKC in cardiomyocyte-like H9c2 cells. EXPERIMENTAL APPROACH: H9c2 cells...

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Detalhes bibliográficos
Main Authors: Almami, Ibtesam, Dickenson, John M, Hargreaves, Alan J, Bonner, Philip L R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128055/
https://ncbi.nlm.nih.gov/pubmed/24821315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12756
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