Polymorphisms in genes related to one-carbon metabolism are not related to pancreatic cancer in PanScan and PanC4

PURPOSE: The evidence of a relation between folate intake and one-carbon metabolism (OCM) with pancreatic cancer (PanCa) is inconsistent. In this study, the association between genes and single-nucleotide polymorphisms (SNPs) related to OCM and PanCa was assessed. METHODS: Using biochemical knowledg...

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Main Authors: Leenders, Max, Bhattacharjee, Samsiddhi, Vineis, Paolo, Stevens, Victoria, Bueno-de-Mesquita, H. Bas, Shu, Xiao-Ou, Amundadottir, Laufey, Gross, Myron, Tobias, Geoffrey S., Wactawski-Wende, Jean, Arslan, Alan A., Duell, Eric J., Fuchs, Charles S., Gallinger, Steven, Hartge, Patricia, Hoover, Robert N., Holly, Elizabeth A., Jacobs, Eric J., Klein, Alison P., Kooperberg, Charles, LaCroix, Andrea, Li, Donghui, Mandelson, Margaret T., Olson, Sara H., Petersen, Gloria, Risch, Harvey A., Yu, Kai, Wolpin, Brian M., Zheng, Wei, Agalliu, Ilir, Albanes, Demetrius, Boutron-Ruault, Marie-Christine, Bracci, Paige M., Buring, Julie E., Canzian, Federico, Chang, Kenneth, Chanock, Stephen J., Cotterchio, Michelle, Gaziano, J. Michael, Giovanucci, Edward L., Goggins, Michael, Hallmans, Göran, Hankinson, Susan E., Hoffman-Bolton, Judith A., Hunter, David J., Hutchinson, Amy, Jacobs, Kevin B., Jenab, Mazda, Khaw, Kay-Tee, Kraft, Peter, Krogh, Vittorio, Kurtz, Robert C., McWilliams, Robert R., Mendelsohn, Julie B., Patel, Alpa V., Rabe, Kari G., Riboli, Elio, Tjønneland, Anne, Trichopoulos, Dimitrios, Virtamo, Jarmo, Visvanathan, Kala, Elena, Joanne W., Yu, Herbert, Zeleniuch-Jacquotte, Anne, Stolzenberg-Solomon, Rachael Z.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127987/
https://ncbi.nlm.nih.gov/pubmed/23334854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10552-012-0138-0
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