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Ultrasensitive immuno-detection using viral nanoparticles with modular assembly using genetically-directed biotinylation
We report a novel, modular approach to immuno-detection based on antibody recognition and PCR read-out that employs antibody-conjugated bacteriophage, easily-manipulated nonpathogenic viruses, as affinity agents. Our platform employs phage genetically tagged for in vivo biotinylation during phage ma...
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| Huvudupphovsmän: | , , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4127420/ https://ncbi.nlm.nih.gov/pubmed/24930095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10529-014-1555-9 |
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