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The identification of a novel SIRT6 modulator from Trigonella foenum-graecum using ligand fishing with protein coated magnetic beads()

SIRT6 is a histone deacetylase that has been proposed as a potential therapeutic target for metabolic disorders and the prevention of age-associated diseases. Thus the identification of compounds that modulate SIRT6 activity could be of great therapeutic importance. We have previously developed an H...

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Detalhes bibliográficos
Main Authors: Singh, N., Ravichandran, S., Spelman, K., Fugmann, S.D., Moaddel, R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127357/
https://ncbi.nlm.nih.gov/pubmed/24704183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2014.03.016
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