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4G/5G Polymorphism of Plasminogen Activator Inhibitor -1 Gene Is Associated with Mortality in Intensive Care Unit Patients with Severe Pneumonia

BACKGROUND: Higher plasma and pulmonary edema fluid levels of plasminogen activator inhibitor-1 (PAI-1) are associated with increased mortality in patients with pneumonia and acute lung injury. The 4G allele of the 4G/5G polymorphism of the PAI-1 gene is associated with higher PAI-1 levels and an in...

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Detalhes bibliográficos
Main Authors: Sapru, Anil, Hansen, Helen, Ajayi, Temitayo, Brown, Ron, Garcia, Oscar, Zhuo, HanJing, Wiemels, Joseph, Matthay, Michael A., Wiener-Kronish, Jeanine
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127307/
https://ncbi.nlm.nih.gov/pubmed/19387177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3181a1081d
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