Murine Aortic Smooth Muscle Cells Acquire, Though Fail to Present Exogenous Protein Antigens on Major Histocompatibility Complex Class II Molecules

In the present study aortic murine smooth muscle cell (SMC) antigen presentation capacity was evaluated using the Eα-GFP/Y-Ae system to visualize antigen uptake through a GFP tag and tracking of Eα peptide/MHCII presentation using the Y-Ae Ab. Stimulation with IFN-γ (100 ng/mL) for 72 h caused a sig...

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Autors principals: Maddaluno, Marcella, MacRitchie, Neil, Grassia, Gianluca, Ialenti, Armando, Butcher, John P., Garside, Paul, Brewer, James M., Maffia, Pasquale
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127268/
https://ncbi.nlm.nih.gov/pubmed/25136640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/949845
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