Expression and Clinical Significance of the Autophagy Proteins BECLIN 1 and LC3 in Ovarian Cancer

Autophagy is dysregulated in cancer and might be involved in ovarian carcinogenesis. BECLIN-1, a protein that interacts with either BCL-2 or PI3k class III, plays a critical role in the regulation of both autophagy and cell death. Induction of autophagy is associated with the presence of vacuoles ch...

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Bibliografiske detaljer
Main Authors: Valente, Guido, Morani, Federica, Nicotra, Giuseppina, Fusco, Nicola, Peracchio, Claudia, Titone, Rossella, Alabiso, Oscar, Arisio, Riccardo, Katsaros, Dyonissios, Benedetto, Chiara, Isidoro, Ciro
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127242/
https://ncbi.nlm.nih.gov/pubmed/25136588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/462658
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