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Syndecan promotes axon regeneration by stabilizing growth cone migration

Growth cones facilitate the repair of nervous system damage by providing the driving force for axon regeneration. Using single-neuron laser axotomy and in vivo time-lapse imaging, we show that syndecan, a heparan sulfate (HS) proteoglycan, is required for growth cone function during axon regeneratio...

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Detalhes bibliográficos
Main Authors: Edwards, Tyson J., Hammarlund, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127196/
https://ncbi.nlm.nih.gov/pubmed/25001284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.06.008
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