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PedBLIMP: Extending Linear Predictors to Impute Genotypes in Pedigrees

Recently, Wen and Stephens [Wen and Stephens 2010] proposed a linear predictor, called BLIMP, that uses conditional multivariate normal moments to impute genotypes with accuracy similar to current state-of-the-art methods. One novelty is that it regularized the estimated covariance matrix based on a...

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Bibliografiske detaljer
Main Authors: Chen, Wenan, Schaid, Daniel J.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127134/
https://ncbi.nlm.nih.gov/pubmed/25044249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21838
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