SDHAF4 promotes mitochondrial succinate dehydrogenase activity and prevents neurodegeneration

Succinate dehydrogenase (SDH) occupies a central place in cellular energy production, linking the tricarboxylic cycle with the electron transport chain. As a result, a subset of cancers and neuromuscular disorders result from mutations affecting any of the four SDH structural subunits or either of t...

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Hlavní autoři: Van Vranken, Jonathan G., Bricker, Daniel K., Dephoure, Noah, Gygi, Steven P., Cox, James E., Thummel, Carl S., Rutter, Jared
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126880/
https://ncbi.nlm.nih.gov/pubmed/24954416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.05.012
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