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Set-Based Joint Test of Interaction Between SNPs in the VEGF Pathway and Exogenous Estrogen Finds Association With Age-Related Macular Degeneration

PURPOSE. Age-related macular degeneration (AMD) is the leading cause of irreversible visual loss in developed countries. Its etiology includes genetic and environmental factors. Although VEGFA variants are associated with AMD, the joint action of variants within the VEGF pathway and their interactio...

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Bibliographische Detailangaben
Hauptverfasser: Courtenay, Monique D., Cade, William H., Schwartz, Stephen G., Kovach, Jaclyn L., Agarwal, Anita, Wang, Gaofeng, Haines, Jonathan L., Pericak-Vance, Margaret A., Scott, William K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126792/
https://ncbi.nlm.nih.gov/pubmed/25015356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14494
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