The Human Antiviral Factor TRIM11 Is under the Regulation of HIV-1 Vpr

TRIM11 has been reported to be able to restrict HIV-1 replication, but the detailed aspects of the interfering mechanisms remain unclear. In this study, we demonstrated that TRIM11 mainly suppressed the early steps of HIV-1 transduction, resulting in decreased reverse transcripts. Additionally, we f...

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Bibliografiske detaljer
Main Authors: Yuan, Ting, Yao, Weitong, Huang, Fang, Sun, Binlian, Yang, Rongge
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126725/
https://ncbi.nlm.nih.gov/pubmed/25105968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104269
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