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Differential Shannon entropy and differential coefficient of variation: alternatives and augmentations to differential expression in the search for disease-related genes

Differential expression has been a standard tool for analysing case-control transcriptomic data since the advent of microarray technology. It has proved invaluable in characterising the molecular mechanisms of disease. Nevertheless, the expression profile of a gene across samples can be perturbed in...

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Detalhes bibliográficos
Main Authors: Wang, Kai, Phillips, Charles A., Rogers, Gary L., Barrenas, Fredrik, Benson, Mikael, Langston, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126647/
https://ncbi.nlm.nih.gov/pubmed/24878729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1504/IJCBDD.2014.061656
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