Accessory cell dependent NK cell mediated PBMC IFN-γ production is defective in HIV infection

HCV and HIV infections impair dendritic cell function. We evaluated the impact of HCV, HIV, and HCV-HIV infection on MDC–NK interactions by analyzing CD3 depleted PBMC for NK cell IFN-γ in response to IL-12 or poly (I:C). Purified MDC and NK cells were analyzed for TLR ligand-dependent, MDC-dependen...

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Main Authors: Yonkers, Nicole L., Milkovich, Kimberly A., Rodriguez, Benigno, Post, Anthony B., Asaad, Robert, Heinzel, Frederick P., Valdez, Hernan, Tary-Lehmann, Magdalena, Anthony, Donald D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126614/
https://ncbi.nlm.nih.gov/pubmed/19196551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2008.12.012
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