Non-additive hepatic gene expression elicited by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and 2,2′,4,4′,5,5′-hexachlorobiphenyl (PCB153) co-treatment in C57BL/6 mice

Interactions between environmental contaminants can lead to non-additive effects that may affect the toxicity and risk assessment of a mixture. Comprehensive time course and dose-response studies with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), non-dioxin-like 2,2′,4,4′,5,5′-hexachlorobiphenyl (PCB1...

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Hauptverfasser: Kopec, Anna K., Souza, Michelle L. D., Mets, Bryan D., Burgoon, Lyle D., Reese, Sarah E., Archer, Kellie J., Potter, Dave, Tashiro, Colleen, Sharratt, Bonnie, Harkema, Jack R., Zacharewski, Timothy R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126514/
https://ncbi.nlm.nih.gov/pubmed/21851831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2011.08.002
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