The algT (algU) gene of Pseudomonas aeruginosa, a key regulator involved in alginate biosynthesis, encodes an alternative sigma factor (sigma E).

Chronic infection by alginate-producing (mucoid) Pseudomonas aeruginosa is the leading cause of mortality among cystic fibrosis (CF) patients. During the course of sustained infection, the production of an alginate capsule protects the bacteria and allows them to persist in the CF lung. One of the k...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Hershberger, C D, Ye, R W, Parsek, M R, Xie, Z D, Chakrabarty, A M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41262/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7644517/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.17.7941
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