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Manganese inhibits mitochondrial aconitase: a mechanism of manganese neurotoxicity()
The symptoms of Mn-induced neurotoxicity resemble those of Parkinson’s diseases. Since iron (Fe) appears to play a pivotal role in pathophysiology of Parkinson’s disease, we set out to test the hypothesis that alterations in Fe-requiring enzymes such as aconitase contribute to Mn-induced neurotoxici...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1998
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4126159/ https://ncbi.nlm.nih.gov/pubmed/9675333 |
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