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Effects of aminoguanidine, a potent nitric oxide synthase inhibitor, on myocardial and organ structure in a rat model of hemorrhagic shock

BACKGROUND: Nitric oxide (NO) has been shown to increase following hemorrhagic shock (HS). Peroxynitrite is produced by the reaction of NO with reactive oxygen species, leads to nitrosative stress mediated organ injury. We examined the protective effects of a potent inhibitor of NO synthase, aminogu...

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Detalhes bibliográficos
Autor principal: Soliman, Mona M.
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126120/
https://ncbi.nlm.nih.gov/pubmed/25114430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0974-2700.136864
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