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Recombinant T-cell Receptor Ligand Treatment Improves Neurological Outcome in the Presence of Tissue Plasminogen Activator in Experimental Ischemic Stroke

RTL1000 is a partial human MHC molecule coupled to a human myelin peptide. We previously demonstrated that RTL1000 was protective against experimental ischemic stroke in HLA-DR2 transgenic (DR2-Tg) mice. Since thrombolysis with recombinant tissue plasminogen activator (t-PA) is a standard therapy fo...

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Detalhes bibliográficos
Main Authors: Zhu, Wenbin, Libal, Nicole L., Casper, Amanda, Bodhankar, Sheetal, Offner, Halina, Alkayed, Nabil J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125526/
https://ncbi.nlm.nih.gov/pubmed/24953050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-014-0348-8
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