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APOε 4 is associated with enhanced in vivo innate immune responses in humans
BACKGROUND: The genetic determinants of the human innate immune response are poorly understood. Apolipoprotein (apo)E, a lipid-trafficking protein that impacts inflammation, has well-described ‘wild type’ (ε3) and disease-associated (ε2, ε4) alleles, but its connection to human innate immunity is un...
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Glavni autori: | , , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2014
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4125509/ https://ncbi.nlm.nih.gov/pubmed/24655576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.01.032 |
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