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Apolipoprotein E receptor-2 deficiency enhances macrophage susceptibility to lipid accumulation and cell death to augment atherosclerotic plaque progression and necrosis

Genome-wide association studies have linked LRP8 polymorphisms to premature coronary artery disease and myocardial infarction in humans. However, the mechanisms by which dysfunctions of apolipoprotein E receptor-2 (apoER2), the protein encoded by LRP8 gene, influence atherosclerosis have not been el...

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Detalhes bibliográficos
Main Authors: Waltmann, Meaghan D., Basford, Joshua E., Konaniah, Eddy S., Weintraub, Neal L., Hui, David Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125478/
https://ncbi.nlm.nih.gov/pubmed/24840660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.05.009
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