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Dating Rare Mutations from Small Samples with Dense Marker Data

We present a method for estimating the age of a mutation based on the genetic length of ancestral haplotypes shared between individuals carrying the mutation. The method can be reliably applied to small samples, typical of situations involving rare mutations, and makes effective use of modern high-d...

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Bibliografische gegevens
Hoofdauteurs: Gandolfo, Luke C., Bahlo, Melanie, Speed, Terence P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Genetics Society of America 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125402/
https://ncbi.nlm.nih.gov/pubmed/24879464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.164616
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