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Dating Rare Mutations from Small Samples with Dense Marker Data
We present a method for estimating the age of a mutation based on the genetic length of ancestral haplotypes shared between individuals carrying the mutation. The method can be reliably applied to small samples, typical of situations involving rare mutations, and makes effective use of modern high-d...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Genetics Society of America
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4125402/ https://ncbi.nlm.nih.gov/pubmed/24879464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.164616 |
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