A Genetic Strategy to Measure Circulating Drosophila Insulin Reveals Genes Regulating Insulin Production and Secretion

Insulin is a major regulator of metabolism in metazoans, including the fruit fly Drosophila melanogaster. Genome-wide association studies (GWAS) suggest a genetic basis for reductions of both insulin sensitivity and insulin secretion, phenotypes commonly observed in humans with type 2 diabetes melli...

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Main Authors: Park, Sangbin, Alfa, Ronald W., Topper, Sydni M., Kim, Grace E. S., Kockel, Lutz, Kim, Seung K.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125106/
https://ncbi.nlm.nih.gov/pubmed/25101872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004555
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