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Playing RNase P Evolution: Swapping the RNA Catalyst for a Protein Reveals Functional Uniformity of Highly Divergent Enzyme Forms

The RNase P family is a diverse group of endonucleases responsible for the removal of 5′ extensions from tRNA precursors. The diversity of enzyme forms finds its extremes in the eukaryal nucleus where RNA-based catalysis by complex ribonucleoproteins in some organisms contrasts with single-polypepti...

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Hlavní autoři: Weber, Christoph, Hartig, Andreas, Hartmann, Roland K., Rossmanith, Walter
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125048/
https://ncbi.nlm.nih.gov/pubmed/25101763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004506
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