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Beyond hypomethylating agents failure in patients with myelodysplastic syndromes

PURPOSE OF REVIEW: Although hypomethylating agents (HMAs) significantly improve outcomes in myelodysplastic syndromes (MDS), only half the patients achieve objective responses, and most responders lose response within 1–2 years. Azacitidine prolongs survival by a median of only 9.5 months. Failure o...

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Hlavní autoři: Zeidan, Amer M., Kharfan-Dabaja, Mohamed A., Komrokji, Rami S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124617/
https://ncbi.nlm.nih.gov/pubmed/24335709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000016
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