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Pedigree and genetic analysis of a novel mutation carrier patient suffering from hereditary nonpolyposis colorectal cancer

AIM: To screen a suspected Hungarian HNPCC family to find specific mutations and to evaluate their effect on the presentation of the disease. METHODS: The family was identified by applying the Amsterdam and Bethesda Criteria. Immunohistochemistry was performed, and DNA samples isolated from tumor ti...

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Hlavní autoři: Tanyi, Miklós, Olasz, Judith, Lukács, Géza, Csuka, Orsolya, Tóth, László, Szentirmay, Zoltán, Ress, Zsuzsa, Barta, Zsolt, Tanyi, János L, Damjanovich, László
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Co., Limited 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124428/
https://ncbi.nlm.nih.gov/pubmed/16534870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i8.1192
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