New Insights into the Role of Mitochondrial Dynamics and Autophagy during Oxidative Stress and Aging in the Heart

The heart is highly sensitive to the aging process. In the elderly, the heart tends to become hypertrophic and fibrotic. Stiffness increases with ensuing systolic and diastolic dysfunction. Aging also affects the cardiac response to stress. At the molecular level, the aging process is associated wit...

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Bibliographic Details
Main Authors: Ikeda, Yoshiyuki, Sciarretta, Sebastiano, Nagarajan, Narayani, Rubattu, Speranza, Volpe, Massimo, Frati, Giacomo, Sadoshima, Junichi
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124219/
https://ncbi.nlm.nih.gov/pubmed/25132912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/210934
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