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New Insights into the Role of Mitochondrial Dynamics and Autophagy during Oxidative Stress and Aging in the Heart

The heart is highly sensitive to the aging process. In the elderly, the heart tends to become hypertrophic and fibrotic. Stiffness increases with ensuing systolic and diastolic dysfunction. Aging also affects the cardiac response to stress. At the molecular level, the aging process is associated wit...

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Detalhes bibliográficos
Main Authors: Ikeda, Yoshiyuki, Sciarretta, Sebastiano, Nagarajan, Narayani, Rubattu, Speranza, Volpe, Massimo, Frati, Giacomo, Sadoshima, Junichi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124219/
https://ncbi.nlm.nih.gov/pubmed/25132912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/210934
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