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Bacteriophage HK022 Nun protein arrests transcription by blocking lateral mobility of RNA polymerase during transcription elongation

Coliphage HK022 excludes phage λ by subverting the λ antitermination system and arresting transcription on the λ chromosome. The 12 kDa HK022 Nun protein binds to λ nascent transcript through its N-terminal Arginine Rich Motif (ARM), blocking access by λ N and arresting transcription via a C-termina...

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Bibliographische Detailangaben
Hauptverfasser: Vitiello, Christal L, Gottesman, Max E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124055/
https://ncbi.nlm.nih.gov/pubmed/25105061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bact.32187
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