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Aliskiren-attenuated myocardium apoptosis via regulation of autophagy and connexin-43 in aged spontaneously hypertensive rats

There are controversies about the mechanism of myocardium apoptosis in hypertensive heart disease. The aim of this study was to investigate the relationship among autophagy, Cx43 and apoptosis in aged spontaneously hypertensive rats (SHRs) and establish whether Aliskiren is effective or not for the...

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Détails bibliographiques
Auteurs principaux: Zhang, Wenbin, Zhao, Gang, Hu, Xiaona, Wang, Min, Li, Hua, Ye, Yong, Du, Qijun, Yao, Jin, Bao, Zhijun, Hong, Wei, Fu, Guosheng, Ge, Junbo, Qiu, Zhaohui
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124010/
https://ncbi.nlm.nih.gov/pubmed/24702827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12273
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