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The human papilloma virus 16E6 gene sensitizes human mammary epithelial cells to apoptosis induced by DNA damage.

Programmed cell death (apoptosis) is a normal physiological process, which could in principle be manipulated to play an important role in cancer therapy. The key importance of p53 expression in the apoptotic response to DNA-damaging agents has been stressed because mutant or deleted p53 is so common...

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Библиографические подробности
Главные авторы: Xu, C, Meikrantz, W, Schlegel, R, Sager, R
Формат: Artigo
Язык:Inglês
Опубликовано: 1995
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC41239/
https://ncbi.nlm.nih.gov/pubmed/7644500
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