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Sphingosine-1-Phosphate Transporters as Targets for Cancer Therapy
Sphingosine-1-phosphate (S1P) is a pleiotropic lipid mediator that regulates cell survival, migration, the recruitment of immune cells, angiogenesis, and lymphangiogenesis, all of which are involved in cancer progression. S1P is generated inside cancer cells by sphingosine kinases then exported outs...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4123566/ https://ncbi.nlm.nih.gov/pubmed/25133174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/651727 |
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