Sphingosine-1-Phosphate Transporters as Targets for Cancer Therapy

Sphingosine-1-phosphate (S1P) is a pleiotropic lipid mediator that regulates cell survival, migration, the recruitment of immune cells, angiogenesis, and lymphangiogenesis, all of which are involved in cancer progression. S1P is generated inside cancer cells by sphingosine kinases then exported outs...

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Autores principales: Nagahashi, Masayuki, Takabe, Kazuaki, Terracina, Krista P., Soma, Daiki, Hirose, Yuki, Kobayashi, Takashi, Matsuda, Yasunobu, Wakai, Toshifumi
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123566/
https://ncbi.nlm.nih.gov/pubmed/25133174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/651727
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