The killing of Leishmania major by human macrophages is mediated by nitric oxide induced after ligation of the Fc epsilon RII/CD23 surface antigen.

Serum IgE concentrations and the expression of the low-affinity receptor for IgE (Fc epsilon RII/CD23) are increased in cutaneous leishmaniasis or after immune challenge with Leishmania antigens. In vitro, the ligation of CD23 by IgE-anti-IgE immune complexes (IgE-IC) or by anti-CD23 monoclonal anti...

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Detalhes bibliográficos
Main Authors: Vouldoukis, I, Riveros-Moreno, V, Dugas, B, Ouaaz, F, Bécherel, P, Debré, P, Moncada, S, Mossalayi, M D
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC41234/
https://ncbi.nlm.nih.gov/pubmed/7544003
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