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Vitamin A dimers trigger the protracted death of retinal pigment epithelium cells

Cellular events responsible for the initiation of major neurodegenerative disorders of the eye leading to blindness, including age-related macular degeneration, Stargardt and Best diseases, are poorly understood. Accumulation of vitamin A dimers, such as N-retinylidene-N-retinylethanolamine (A2E) in...

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Detalhes bibliográficos
Main Authors: Mihai, D M, Washington, I
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123103/
https://ncbi.nlm.nih.gov/pubmed/25058422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.314
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