FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway

Ovarian cancer (OC) can be classified into five biologically distinct molecular subgroups: epithelial-A (Epi-A), Epi-B, mesenchymal (Mes), Stem-A and Stem-B. Among them, Stem-A expresses genes relating to stemness and is correlated with poor clinical prognosis. In this study, we show that frizzled f...

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Detalhes bibliográficos
Main Authors: Asad, M, Wong, M K, Tan, T Z, Choolani, M, Low, J, Mori, S, Virshup, D, Thiery, J P, Huang, R Y-J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123093/
https://ncbi.nlm.nih.gov/pubmed/25032869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.302
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