Na(V)1.5 sodium channel window currents contribute to spontaneous firing in olfactory sensory neurons

Olfactory sensory neurons (OSNs) fire spontaneously as well as in response to odor; both forms of firing are physiologically important. We studied voltage-gated Na(+) channels in OSNs to assess their role in spontaneous activity. Whole cell patch-clamp recordings from OSNs demonstrated both tetrodot...

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Detalhes bibliográficos
Main Authors: Frenz, Christopher T., Hansen, Anne, Dupuis, Nicholas D., Shultz, Nicole, Levinson, Simon R., Finger, Thomas E., Dionne, Vincent E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Cellular and Molecular Properties of Neurons
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122723/
https://ncbi.nlm.nih.gov/pubmed/24872539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00154.2014
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