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Brains in metamorphosis: reprogramming cell identity within the central nervous system

During embryonic development, uncommitted pluripotent cells undergo progressive epigenetic changes that lock them into a final differentiated state. Can mammalian cells change identity within the living organism? Direct lineage reprogramming of cells has attracted attention as a means to achieve org...

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Detalhes bibliográficos
Main Authors: Arlotta, Paola, Berninger, Benedikt
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122594/
https://ncbi.nlm.nih.gov/pubmed/24800935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conb.2014.04.007
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