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New drugs to treat multidrug-resistant tuberculosis: the case for bedaquiline

Mycobacterium tuberculosis develops spontaneous resistance mutants to virtually every drug in use. Courses of therapy select for these mutants and drug-resistant organisms emerge. The development of drug-resistant organisms has reached the point that drug resistance now threatens to undermine global...

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Bibliografiske detaljer
Main Authors: Leibert, Eric, Danckers, Mauricio, Rom, William N
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122575/
https://ncbi.nlm.nih.gov/pubmed/25114537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S37743
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