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Emerging FMS-like tyrosine kinase 3 inhibitors for the treatment of acute myelogenous leukemia

INTRODUCTION: The FMS-like tyrosine kinase 3 (FLT3) is highly expressed in acute leukemias. Mutations involving FLT3 are among the most common molecular abnormalities in acute myelogenous leukemia (AML). Available evidence suggests that these molecular lesions confer a shorter disease-free survival...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Prescott, Hillary, Kantarjian, Hagop, Cortes, Jorge, Ravandi, Farhad
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122233/
https://ncbi.nlm.nih.gov/pubmed/21417961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728214.2011.568938
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