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Dynamic myosin phosphorylation regulates contractile pulses and tissue integrity during epithelial morphogenesis

Apical constriction is a cell shape change that promotes epithelial bending. Activation of nonmuscle myosin II (Myo-II) by kinases such as Rho-associated kinase (Rok) is important to generate contractile force during apical constriction. Cycles of Myo-II assembly and disassembly, or pulses, are asso...

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Bibliographic Details
Main Authors: Vasquez, Claudia G., Tworoger, Mike, Martin, Adam C.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121972/
https://ncbi.nlm.nih.gov/pubmed/25092658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201402004
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