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Heterocyclic aminoparthenolide derivatives modulate G(2)-M cell progression during Xenopus oocyte maturation

Aminoparthenolide derivatives have been prepared by reaction of parthenolide with various heterocyclic amines to afford corresponding Michael addition products. These novel compounds were evaluated for their modulatory effects on Xenopus oocyte maturation. Two compounds, 6e and 6f, were identified t...

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Autors principals: Janganati, Venumadhav, Penthala, Narsimha Reddy, Cragle, Chad E., MacNicol, Angus M., Crooks, Peter A.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121966/
https://ncbi.nlm.nih.gov/pubmed/24656611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.02.067
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