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EBV microRNA BART 18-5p targets MAP3K2 to facilitate persistence in vivo by inhibiting viral replication in B cells

EBV is an oncogenic human herpesvirus that has the ability to infect and transform B cells latently in vitro. However, the virus also establishes a lifetime, benign, persistent latent infection in resting memory B cells in vivo, where the virus is quiescent (i.e., expresses none of the known latent...

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Detalhes bibliográficos
Main Authors: Qiu, Jin, Thorley-Lawson, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121837/
https://ncbi.nlm.nih.gov/pubmed/25012295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406136111
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