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Intraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgery

For many intraoperative decisions surgeons depend on frozen section pathology, a technique developed over 150 y ago. Technical innovations that permit rapid molecular characterization of tissue samples at the time of surgery are needed. Here, using desorption electrospray ionization (DESI) MS, we ra...

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Detalhes bibliográficos
Main Authors: Santagata, Sandro, Eberlin, Livia S., Norton, Isaiah, Calligaris, David, Feldman, Daniel R., Ide, Jennifer L., Liu, Xiaohui, Wiley, Joshua S., Vestal, Matthew L., Ramkissoon, Shakti H., Orringer, Daniel A., Gill, Kristen K., Dunn, Ian F., Dias-Santagata, Dora, Ligon, Keith L., Jolesz, Ferenc A., Golby, Alexandra J., Cooks, R. Graham, Agar, Nathalie Y. R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121790/
https://ncbi.nlm.nih.gov/pubmed/24982150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404724111
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