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A New Strategy to Deliver Synthetic Protein Drugs: Self-reproducible Biologics Using Minicircles

Biologics are the most successful drugs used in anticytokine therapy. However, they remain partially unsuccessful because of the elevated cost of their synthesis and purification. Development of novel biologics has also been hampered by the high cost. Biologics are made of protein components; thus,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yi, Hyoju, Kim, Youngkyun, Kim, Juryun, Jung, Hyerin, Rim, Yeri Alice, Jung, Seung Min, Park, Sung-Hwan, Ju, Ji Hyeon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121613/
https://ncbi.nlm.nih.gov/pubmed/25091294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05961
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