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Targeting IL-4/IL-13 signaling to alleviate oral allergen-induced diarrhea
RATIONALE: Intestinal anaphylaxis (manifested by acute diarrhea) is dependent on IgE and mast cells. OBJECTIVE: We aimed to define the respective roles of IL-4 and IL-13 and their receptors in disease pathogenesis. METHODS: Wild-type mice and mice deficient in IL-4, IL-13, and IL-13Rα1 (part of the...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4121593/ https://ncbi.nlm.nih.gov/pubmed/18996576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2008.10.001 |
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